When the body encounters a viral infection such as a cold or flu, a complex immune cascade is activated. This response involves inflammatory signaling molecules, increased lymphatic activity, vascular changes, and heightened metabolic demand. Symptoms like sore throat, congestion, headache, and fatigue are not the illness itself, but the body’s inflammatory and immune response to it.
Topical plant-based compounds can support these physiological processes by interacting with the skin, nervous system, and immune pathways. Castor oil, derived from Ricinus communis, is one of the most extensively used traditional oils for this purpose and is now gaining renewed scientific interest.
At iAMA, our castor oil is organic, cold-pressed, hexane-free, and unrefined, preserving its full biochemical profile so it can work synergistically with the body during immune stress.
Biochemical Composition of Castor Oil
Castor oil is unique among plant oils due to its exceptionally high concentration of ricinoleic acid, which constitutes approximately 90% of its fatty acid content. Ricinoleic acid is a monounsaturated omega-9 fatty acid with hydroxyl functionality, which gives castor oil its distinctive viscosity and biological activity.
In addition to ricinoleic acid, iAMA castor oil contains:
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Oleic acid – enhances skin permeability and transdermal absorption
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Linoleic acid – supports epidermal barrier repair and modulates inflammation
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Stearic and palmitic acids – contribute to tissue lubrication and protection
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Vitamin E (tocopherols) – provides antioxidant defense against oxidative stress
Because iAMA castor oil is cold-pressed and solvent-free, these compounds remain intact and bioactive.
Anti-Inflammatory Mechanisms and Immune Modulation
Inflammation during viral illness is mediated largely by prostaglandins and cytokines, signaling molecules produced through pathways involving cyclooxygenase (COX) enzymes.
Research indicates that ricinoleic acid inhibits prostaglandin E2 (PGE2) synthesis, a key mediator of pain, swelling, and redness. By reducing excessive inflammatory signaling, castor oil may help modulate tissue irritation without suppressing the immune response itself.
Additionally, ricinoleic acid has been shown to interact with EP3 prostanoid receptors, which play a role in pain perception and immune regulation. This receptor interaction may explain castor oil’s traditional use for soothing discomfort associated with sore throat, chest tightness, and headaches.
Lymphatic System Support and Detoxification Pathways
The lymphatic system is central to immune defense. It transports immune cells, clears metabolic waste, and removes viral debris. During illness, lymph flow can become sluggish, contributing to swelling, tenderness, and prolonged congestion.
Topical castor oil application has been associated with:
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Increased lymphocyte circulation
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Enhanced lymphatic drainage
- Reduced tissue edema
This effect is thought to occur through vasodilation, local warmth, and mechanical stimulation during massage, combined with castor oil’s ability to penetrate the skin barrier and influence underlying tissues.
By supporting lymphatic movement, castor oil may help the body resolve inflammation more efficiently.
Skin as an Immune and Neuroendocrine Organ
The skin is not merely a barrier; it is an active immune and neuroendocrine organ rich in sensory nerve endings, immune cells, and hormone receptors. When castor oil is applied topically, it interacts with:
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Keratinocytes, which regulate immune signaling
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Mast cells, which influence inflammation
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TRPV1 receptors, involved in pain and temperature perception
This interaction may help explain why castor oil application to the throat, chest, and temples can produce systemic calming effects, including reduced pain sensitivity and muscular tension.
Targeted Application for Cold and Flu Support
Throat and Cervical Lymph Nodes
Applying iAMA castor oil to the anterior neck targets tissues near the tonsils, thyroid, and cervical lymph nodes. This may support immune traffic and reduce localized inflammation contributing to sore throat discomfort.
Here's how to use castor oil with gua sha: https://iamawellness.com/blogs/news/face-sculpting-with-gua-sha-with-castor-oil
Chest and Upper Back
The lungs are surrounded by lymph-rich tissue. Castor oil massage over the chest and upper back supports circulation, tissue relaxation, and lymphatic drainage, particularly when paired with warmth.
Temples and Sinus Regions
Sinus pressure is often driven by vascular inflammation and fluid buildup. Castor oil’s fatty acid profile supports nerve modulation and microcirculation, which may ease tension headaches and sinus discomfort.
Here's how to apply castor oil as a pack: https://iamawellness.com/blogs/news/the-ultimate-guide-to-castor-oil-packing
Why iAMA Castor Oil Is Biologically Superior
Many castor oils on the market are refined, deodorized, or extracted using chemical solvents. These processes degrade fatty acids and reduce bioactivity.
iAMA castor oil is:
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Cold-pressed, preserving fatty acid integrity
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Hexane-free, avoiding solvent residue
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Organic, ensuring no pesticide interference with immune pathways
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Glass-bottled, protecting oil stability
This purity ensures optimal interaction with the skin, lymphatic system, and immune response - especially important when the body is already under stress.
Supporting Physiological Balance During Illness
Castor oil does not function as an antiviral or medication. Instead, it supports homeostasis - the body’s ability to maintain balance while fighting infection. By modulating inflammation, enhancing lymphatic flow, and calming overactive pain signaling, castor oil works with the body rather than overriding it.
During cold and flu season, simple, biologically compatible interventions often have the greatest impact. iAMA castor oil offers a scientifically grounded, time-honored way to support your body’s innate healing intelligence.
References
Effect of ricinoleic acid in acute and subchronic experimental models of inflammation https://pmc.ncbi.nlm.nih.gov/articles/PMC1781768/
A mechanism for reducing inflammation and irritation in tissues https://pmc.ncbi.nlm.nih.gov/articles/PMC1781768/
Castor Oil: What are its active molecules? https://uk.typology.com/library/what-is-the-composition-of-castor-oil
